First signs of pancreatitis in dogs
No single sign is specific. Common signs are loss of appetite, vomiting, weakness, diarrhoea and nausea (lip licking, drooling); some dogs stand in a “prayer position” because of belly pain [1]. In a study of 170 dogs with a raised pancreatic lipase, poor appetite was seen in 62%, diarrhoea in 53%, vomiting in 49% and belly pain in only 32% [2].
Risk factors
- Food: raiding the rubbish multiplied the risk by about 13 in one study; unusual food items and table scraps also raised it [3].
- Breed: Miniature Schnauzers, Miniature Poodles, Yorkshire and other terriers, Dachshunds and Cocker Spaniels are over-represented in acute pancreatitis [3].
- Other diseases: high triglycerides, Cushing’s disease, hypothyroidism and diabetes; diabetic dogs had a 12.4 times higher risk of pancreatitis [1, 3].
- Overweight and some medicines [3].
The pancreas tests
| Test | What the result means | Limits |
|---|---|---|
| Spec cPL (laboratory) | 200 µg/L or less: normal; 201–399: equivocal, repeat; 400 or more: highly suggestive [1]. | Can miss mild pancreatitis and rise in other diseases [1]. |
| SNAP cPL (in clinic) | Normal or abnormal. | Reads abnormal from the equivocal zone: a positive is confirmed with Spec cPL [1]. |
| Lipase on the panel (DGGR) | High in many dogs with pancreatitis. | Not specific to the pancreas [1]. |
| Amylase | No longer used for the diagnosis. | Raised by kidney disease; poor sensitivity [1]. |
Lipase can be high without pancreatitis, for example with kidney disease, heart disease, Cushing’s disease or corticosteroids [1]. See lipase and amylase.
How to read the Spec cPL line
Here is an example result in a vomiting dog.
What routine blood work shows
- Dehydration: a high haematocrit and high kidney values, which can also reflect kidney injury [1].
- White cells: often an inflammatory pattern with young neutrophils [1]. See white blood cell count.
- Liver values: ALT, ALP and GGT often rise; sometimes bilirubin, if the bile duct is blocked [1]. See high liver enzymes.
- Triglycerides may be high [3]. See cholesterol and triglycerides.
- Low platelets in severe cases can signal a clotting complication [1].
The role of the ultrasound
An abdominal ultrasound looks for an enlarged pancreas, bright surrounding fat and fluid. Its accuracy depends on how many changes are required, and changes can appear only after a few days [1]. Blood tests and imaging should not be used in isolation [1].
Related articles
En français : la pancréatite du chien.
For cats, see pancreatitis in cats.
Questions to ask your veterinarian
- Was the lipase on the report a Spec cPL or a routine lipase?
- Does the ultrasound support pancreatitis?
- How severe is it, based on the blood work?
- Could high triglycerides, Cushing’s or diabetes be involved?
- Which diet and follow-up do you recommend afterwards?
Get your dog’s pancreas and chemistry results explained together.
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Frequently asked questions
What are the first signs of pancreatitis in a dog?
Loss of appetite, vomiting, diarrhoea and weakness are the most common; belly pain is noticed in only about a third of dogs [1, 2].
What foods can cause pancreatitis in dogs?
Raiding the rubbish, fatty foods, unusual items and table scraps were all linked to a higher risk in one study [3].
Are Poodles prone to pancreatitis?
Miniature Poodles are among the breeds over-represented in acute pancreatitis, along with Miniature Schnauzers and terriers [3].
How is chronic pancreatitis managed in dogs?
With diet changes, treatment of flare-ups and of associated diseases such as high triglycerides, under your vet’s guidance.
Can a high lipase mean something other than pancreatitis?
Yes. Kidney disease, heart disease, Cushing’s disease and corticosteroids can raise lipase. Signs and ultrasound are needed to conclude [1].
Sources
- Cridge H et al. Advances in the diagnosis of acute pancreatitis in dogs. J Vet Intern Med. 2021;35(6):2572-2587. doi.org/10.1111/jvim.16292
- Cridge H et al. Risk factors and clinical presentation in dogs with increased serum pancreatic lipase concentrations: a descriptive analysis. Animals (Basel). 2022;12(12):1581. doi.org/10.3390/ani12121581
- Cridge H et al. New insights into the etiology, risk factors, and pathogenesis of pancreatitis in dogs: potential impacts on clinical practice. J Vet Intern Med. 2022;36(3):847-864. doi.org/10.1111/jvim.16437
Laboratory methods and reference intervals vary. This article explains; it does not diagnose. For a decision about your pet, use the original report and talk to your veterinarian. Our editorial policy.